Immunomodulatory effects of marine polysaccharides
A rising number of reports associate synthetic drugs with adverse reactions and drug toxicity. Marine polysaccharides may offer effective and non-toxic solutions. A recently published paper noted the advantages of exploring the potential of natural therapeutics, particularly the unique bioactive compounds that marine algae possess.
The paper summarized the chemical composition of a range of marine polysaccharides, including fucoidan, and discussed their potential applications in relation to cancer, infectious disease and inflammation.
The review summarised previous research in which polysaccharides from seaweeds have been shown to have immunomodulatory effects as well as potentially possessing antiviral, anticancer and antioxidant properties. The review also noted that some molecules that participate in immune activation may induce immune responses against cancer and infectious diseases.
A range of potential nutraceuticals and pharmaceutical applications for marine polysaccharides were discussed in the paper. Particular attention was paid to the future manufacture of nanoparticles to potentially assist in the treatment of various diseases.
The paper, ‘Immunomodulatory effects of polysaccharides from marine algae for treating cancer, infectious disease and inflammation’ was published in the journal Phytotherapy Research.